Jiun-Cheng Jiang
Publications
Complementary Matrix-Gated QKAN Fast-Weight Programmers for Quantum Dynamics Forecasting
Sequence models must decide what to write into memory and what to retain. In quantum and quantum-inspired sequence learning, nonlinear recurrent updates often require repeated circuit evaluations and sequential backpropagation through time, making long contexts costly. Gated fast-weight programmers (FWPs) based on quantum-inspired Kolmogorov-Arnold networks (QKANs) alleviate this bottleneck by storing context in time-varying fast parameters. However, their scalar gate applies one retention-write balance to every fast-state coordinate, forcing all parameters to share a memory timescale. We introduce Self-Modulating QKAN-based FWPs, which replace this broadcast gate with low-rank-generated element-wise modulation of the new-proposal branch, a bounded old-state branch, or both. We further propose Complementary Matrix Gating (CMG), which uses one sigmoid matrix gate to retain the old state and its complement to write the new proposal. CMG provides coordinate-wise memory control while preserving the bounded convex update and affine prefix-scan structure of scalar gating, at the modulation-head cost of a single-branch rule. We compare four self-modulating rules with scalar gating across four FWP architectures combining classical and QKAN-based slow and fast programmers. Across seven single-step forecasting benchmarks and five sequence lengths, CMG gives the most consistent improvements for architectures whose fast programmer incorporates a QKAN-based module. In direct multi-step forecasting of Jaynes-Cummings and transmon-resonator dynamics simulated with CUDA-Q Dynamics, CMG models maintain mean-squared errors on the order of 0.001 or lower across forecasting horizons of 4, 8, and 16 steps, while improving on their scalar-gated counterparts by at least 91.2%. These results establish coordinate-wise complementary modulation as a stable and effective update for QKAN-based FWPs.
NVAITC AI Scientist: A Governed End-to-End Research System -- A Hypertension GWAS Case Study
Agentic research systems are emerging as a new paradigm for coordinating scientific workflows beyond isolated model inference, code generation, or statistical analysis. However, deployment in institutional biomedical environments requires governed mechanisms for research planning, data access, workflow orchestration, evidence tracking, reproducibility, and human oversight. We present NVAITC AI Scientist (NAIS), a governed end-to-end agentic research system designed to support domain-general scientific workflows while keeping protected data within institutional privacy boundaries. NAIS integrates proposal review, execution planning, governed computational routing, reproducible workflow orchestration, evidence generation, and scientist-in-the-loop oversight. We validate NAIS in a real-world hypertension genome-wide association study (GWAS) using hospital-linked genotype and electronic health record (EHR) data from 286,422 individuals under an aggregate-only data policy. The agent planned cohort extraction, orchestrated GWAS execution, generated quality-control summaries, and drafted publication-oriented outputs. Human-AI review identified phenotype discrepancies and enabled iterative refinement of the hypertension definition. After reconciliation, the agent-orchestrated GWAS reproduced established hypertension loci, including FGF5, ATP2B1, CNNM2, FTO, and GRB14, with the strongest signal at FGF5 reaching $-\log_{10}(p) \sim 70$. As a secondary demonstration, NAIS also supported a drug-induced liver injury prediction workflow, achieving a multimodal graph neural network AUC of 0.842. These results demonstrate that governed agentic research systems can support scalable AI-assisted biomedical discovery while producing outputs comparable to expert-led workflows.
Stable Self-Modulating Quantum Fast-Weight Programmers with Bounded Memory Gates
Quantum Fast-Weight Programmers (QFWPs) store temporal information in dynamically programmed variational-circuit parameters rather than in nonlinear recurrent hidden states, offering a practical route to quantum sequence modeling. Self-Modulating QFWP improves this framework by using input-dependent gates for both new fast-weight updates and the accumulated fast-weight state, but its unbounded old-state multiplier can diverge in long-sequence regimes. We propose a bounded old-state modulation rule that applies a sign-preserving tanh gate only to the recurrent memory branch while leaving the additive update and new-update modulation unchanged. We evaluate standard QFWP, full Self-Modulating QFWP, Only-New, and Only-Old variants on two CUDA-Q quantum-dynamics forecasting tasks and on Milan SMS telecommunication activity prediction. The quantum-dynamics results show that old-state modulation is the most consistent source of improvement over Standard QFWP, and that bounding the old-state gate removes long-sequence divergence while improving aggregate robustness. On Milan SMS forecasting, the original unbounded Self-Modulating QFWP converges across the tested grid and shows its clearest gains at longer input windows, with behavior close to the Only-Old ablation. These findings identify accumulated-memory modulation as the key mechanism of Self-Modulating QFWP and bounded old-state gating as a targeted stabilization strategy.