Weiran Liao
Publications
RayViT: Ray-Conditioned Visual Representations for Viewpoint-Robust Imitation Learning
Visual imitation learning enables robots to acquire visuomotor skills directly from images, yet RGB observations lack explicit geometric cues, making learned policies brittle to camera perturbations. To address this, we propose \textbf{Ray-conditioned Vision Transformer Encoder (RayViT)}, a lightweight architecture that injects camera geometry into pretrained ViT backbones. RayViT represents camera geometry as a Plücker ray map, patchifies it into ray features, and uses gated cross-attention to produce a ray-conditioned class token. These ray features are added as dense positional embeddings, while the ray class token replaces the original ViT class token to provide a geometry-aware summary representation. We combine this approach with an auxiliary cosine similarity loss to consistently improve the performance and robustness for geometry-aware tokens. Experiments on sim- and real-robot tasks demonstrate that RayViT improves robustness by approximately 13 percentage points under camera perturbations in multi-task RoboCasa benchmark and by 1.78 average completed stages in real-world multi-task success rate compared to baselines.
DeepBD: A Grounded Agentic Workflow for Variant Prioritization and Diagnosis of Genetic Birth Defects
Birth defects are a major cause of fetal loss, neonatal morbidity and long-term disability. In the subset with suspected genetic etiologies, exome and genome sequencing have moved many cases from variant detection to post-sequencing interpretation: clinicians must rank patient-specific candidate variants under incomplete fetal or infant phenotypes and heterogeneous evidence from population genetics, variant-effect prediction, gene-disease validity, phenotype ontologies, cellular and pathway context, protein structure and clinical literature. We present DeepBD, a grounded agentic workflow for variant prioritization and diagnostic interpretation of genetic birth defects. DeepBD organizes the workflow into LLM-assisted case structuring, a pretrained evidence engine, specialist evidence modules and a grounded diagnostic review layer. The evidence engine learns patient-specific variant scores from structured rule evidence, sequence and variant-effect representations and phenotype-conditioned biological context, whereas specialist modules and the agentic layer provide tool-based refinement, candidate-pool review and diagnosis-oriented synthesis from ranked candidates. Developed using an in-house fetal and infant cohort comprising 18,622 cases, DeepBD achieved Recall@1/3/5/10 of 0.658/0.882/0.912/0.929 on an internal held-out solved-case benchmark, outperforming standalone Exomiser, DeepRare and prompted LLM reranking baselines evaluated on Exomiser-derived top-20 candidate variants. Ablation and overlap analyses show that rule evidence, mechanistic context, and specialist refinement provide complementary signals. These findings support a grounded agentic workflow that separates evidence integration, tool-based refinement, and LLM-assisted diagnostic review for retrospective variant prioritization in genetic birth defects.