Xiaobin Hu
Publications
PASK: Toward Intent-Aware Proactive Agents with Long-Term Memory
Proactivity is a core expectation for AGI. Prior work remains largely confined to laboratory settings, leaving a clear gap in real-world proactive agent: depth, complexity, ambiguity, precision and real-time constraints. We study this setting, where useful intervention requires inferring latent needs from ongoing context and grounding actions in evolving user memory under latency and long-horizon constraints. We first propose DD-MM-PAS (Demand Detection, Memory Modeling, Proactive Agent System) as a general paradigm for streaming proactive AI agent. We instantiate this paradigm in Pask, with streaming IntentFlow model for DD, a hybrid memory (workspace, user, global) for long-term MM, PAS infra framework and introduce how these components form a closed loop. We also introduce LatentNeeds-Bench, a real-world benchmark built from user-consented data and refined through thousands of rounds of human editing. Experiments show that IntentFlow matches leading Gemini3-Flash models under latency constraints, while identifying deeper user intent.
TheraAgent: Multi-Agent Framework with Self-Evolving Memory and Evidence-Calibrated Reasoning for PET Theranostics
PET theranostics is transforming precision oncology, yet treatment response varies substantially; many patients receiving 177Lu-PSMA radioligand therapy (RLT) for metastatic castration-resistant prostate cancer (mCRPC) fail to respond, demanding reliable pre-therapy prediction. While LLM-based agents have shown remarkable potential in complex medical diagnosis, their application to PET theranostic outcome prediction remains unexplored, which faces three key challenges: (1) data and knowledge scarcity: RLT was only FDA-approved in 2022, yielding few training cases and insufficient domain knowledge in general LLMs; (2) heterogeneous information integration: robust prediction hinges on structured knowledge extraction from PET/CT, laboratory tests, and free-text clinical documentation; (3) evidence-grounded reasoning: clinical decisions must be anchored in trial evidence rather than LLM hallucinations. In this paper, we present TheraAgent, to our knowledge, the first agentic framework for PET theranostics, with three core innovations: (1) Multi-Expert Feature Extraction with Confidence-Weighted Consensus, where three specialized experts process heterogeneous inputs with uncertainty quantification; (2) Self-Evolving Agentic Memory (SEA-Mem), which learns prognostic patterns from accumulated cases, enabling case-based reasoning from limited data; (3) Evidence-Calibrated Reasoning, integrating a curated theranostics knowledge base to ground predictions in VISION/TheraP trial evidence. Evaluated on 35 real patients and 400 synthetic cases, TheraAgent achieves 75.7% overall accuracy on real patients and 87.0% on synthetic cases, outperforming MDAgents and MedAgent-Pro by over 20%. These results highlight a promising blueprint for trustworthy AI agents in PET theranostics, enabling trial-calibrated, multi-source decision support. Code will be released upon acceptance.
Dual Latent Memory for Visual Multi-agent System
While Visual Multi-Agent Systems (VMAS) promise to enhance comprehensive abilities through inter-agent collaboration, empirical evidence reveals a counter-intuitive "scaling wall": increasing agent turns often degrades performance while exponentially inflating token costs. We attribute this failure to the information bottleneck inherent in text-centric communication, where converting perceptual and thinking trajectories into discrete natural language inevitably induces semantic loss. To this end, we propose L$^{2}$-VMAS, a novel model-agnostic framework that enables inter-agent collaboration with dual latent memories. Furthermore, we decouple the perception and thinking while dynamically synthesizing dual latent memories. Additionally, we introduce an entropy-driven proactive triggering that replaces passive information transmission with efficient, on-demand memory access. Extensive experiments among backbones, sizes, and multi-agent structures demonstrate that our method effectively breaks the "scaling wall" with superb scalability, improving average accuracy by 2.7-5.4% while reducing token usage by 21.3-44.8%. Codes: https://github.com/YU-deep/L2-VMAS.