Menglin Yang
Publications
Continuous Knowledge Metabolism: Generating Scientific Hypotheses from Evolving Literature
Scientific hypothesis generation requires tracking how knowledge evolves, not just what is currently known. We introduce Continuous Knowledge Metabolism (CKM), a framework that processes scientific literature through sliding time windows and incrementally updates a structured knowledge base as new findings arrive. We present CKM-Lite, an efficient variant that achieves strong predictive coverage through incremental accumulation, outperforming batch processing on hit rate (+2.8%, p=0.006), hypothesis yield (+3.6, p<0.001), and best-match alignment (+0.43, p<0.001) while reducing token cost by 92%. To understand what drives these differences, we develop CKM-Full, an instrumented variant that categorizes each new finding as novel, confirming, or contradicting, detects knowledge change signals, and conditions hypothesis generation on the full evolution trajectory. Analyzing 892 hypotheses generated by CKM-Full across 50 research topics, alongside parallel runs of the other variants, we report four empirical observations: (1) incremental processing outperforms batch baseline across predictive and efficiency metrics; (2) change-aware instrumentation is associated with higher LLM-judged novelty (Cohen's d=3.46) but lower predictive coverage, revealing a quality-coverage trade-off; (3) a field's trajectory stability is associated with hypothesis success (r=-0.28, p=0.051), suggesting boundary conditions for literature-based prediction; (4) knowledge convergence signals are associated with nearly 5x higher hit rate than contradiction signals, pointing to differential predictability across change types. These findings suggest that the character of generated hypotheses is shaped not only by how much literature is processed, but also by how it is processed. They further indicate that evaluation frameworks must account for the quality-coverage trade-off rather than optimize for a single metric.
TurboEvolve: Towards Fast and Robust LLM-Driven Program Evolution
LLM-driven program evolution can discover high-quality programs, but its cost and run-to-run variance hinder reliable progress. We propose TurboEvolve, a multi-island evolutionary framework that improves sample efficiency and robustness under fixed evaluation budgets. Inspired by the multiple-offspring strategy in evolutionary algorithms, TurboEvolve introduces verbalized Sampling, prompting the LLM to emit K diverse candidates with explicit self-assigned sampling weights, and an online scheduler that adapts K to expand exploration under stagnation and reduce overhead during steady progress. To exploit existing solution pools, we further propose "seed-pool injection," which clusters seeds and assigns them across islands with controlled perturbations and elitist preservation to balance diversity and refinement. Across multiple program-optimization benchmarks, TurboEvolve consistently achieves stronger performance at lower budgets and improves best-known solutions on several tasks.