Patrick Vossler
Publications
More Than "Means to an End": Supporting Reasoning with Transparently Designed AI Data Science Processes
Generative artificial intelligence (AI) tools can now help people perform complex data science tasks regardless of their expertise. While these tools have great potential to help more people work with data, their end-to-end approach does not support users in evaluating alternative approaches and reformulating problems, both critical to solving open-ended tasks in high-stakes domains. In this paper, we reflect on two AI data science systems designed for the medical setting and how they function as tools for thought. We find that success in these systems was driven by constructing AI workflows around intentionally-designed intermediate artifacts, such as readable query languages, concept definitions, or input-output examples. Despite opaqueness in other parts of the AI process, these intermediates helped users reason about important analytical choices, refine their initial questions, and contribute their unique knowledge. We invite the HCI community to consider when and how intermediate artifacts should be designed to promote effective data science thinking.
Human-AI Co-design for Clinical Prediction Models
Developing safe, effective, and practically useful clinical prediction models (CPMs) traditionally requires iterative collaboration between clinical experts, data scientists, and informaticists. This process refines the often small but critical details of the model building process, such as which features/patients to include and how clinical categories should be defined. However, this traditional collaboration process is extremely time- and resource-intensive, resulting in only a small fraction of CPMs reaching clinical practice. This challenge intensifies when teams attempt to incorporate unstructured clinical notes, which can contain an enormous number of concepts. To address this challenge, we introduce HACHI, an iterative human-in-the-loop framework that uses AI agents to accelerate the development of fully interpretable CPMs by enabling the exploration of concepts in clinical notes. HACHI alternates between (i) an AI agent rapidly exploring and evaluating candidate concepts in clinical notes and (ii) clinical and domain experts providing feedback to improve the CPM learning process. HACHI defines concepts as simple yes-no questions that are used in linear models, allowing the clinical AI team to transparently review, refine, and validate the CPM learned in each round. In two real-world prediction tasks (acute kidney injury and traumatic brain injury), HACHI outperforms existing approaches, surfaces new clinically relevant concepts not included in commonly-used CPMs, and improves model generalizability across clinical sites and time periods. Furthermore, HACHI reveals the critical role of the clinical AI team, such as directing the AI agent to explore concepts that it had not previously considered, adjusting the granularity of concepts it considers, changing the objective function to better align with the clinical objectives, and identifying issues of data bias and leakage.