Max Van Puyvelde
Publications
OpenMedQ: Broad Open Pretraining for Medical Vision-Language Models
We present OpenMedQ, a medical vision-language model pretrained on the broadest fully-open medical mix to date: 14 datasets totaling ~3.35M pretraining samples spanning pathology, radiology, microscopy, and text-only clinical QA. OpenMedQ reaches state-of-the-art BLEU-1 on PathVQA (75.9), beating Med-PaLM M variants up to 562B parameters (~80x larger), and matches the best reported VQA-MED BLEU-1 (64.5). Its vision encoder, transferred to 8 unseen medical classification benchmarks under an identical downstream recipe, obtains the highest average macro-F1 (0.757) among BiomedCLIP (0.745), PMC-CLIP (0.745), PubMedCLIP (0.746), and a from-scratch baseline (0.616). We release our code and an interactive demo is publicly available as a reproducible baseline for the community.
Compiled AI: Deterministic Code Generation for LLM-Based Workflow Automation
We study compiled AI, a paradigm in which large language models generate executable code artifacts during a compilation phase, after which workflows execute deterministically without further model invocation. This paradigm has antecedents in prior work on declarative pipeline optimization (DSPy) and hybrid neural-symbolic planning (LLM+P); our contribution is a systems-oriented study of its application to high-stakes enterprise workflows, with particular emphasis on healthcare settings where reliability and auditability are critical. By constraining generation to narrow business-logic functions embedded in validated templates, compiled AI trades runtime flexibility for predictability, auditability, cost efficiency, and reduced security exposure. We introduce (i) a system architecture for constrained LLM-based code generation, (ii) a four-stage generation-and-validation pipeline that converts probabilistic model output into production-ready code artifacts, and (iii) an evaluation framework measuring operational metrics including token amortization, determinism, reliability, security, and cost. We evaluate on two task types: function-calling (BFCL, n=400) and document intelligence (DocILE, n=5,680 invoices). On function-calling, compiled AI achieves 96% task completion with zero execution tokens, breaking even with runtime inference at approximately 17 transactions and reducing token consumption by 57x at 1,000 transactions. On document intelligence, our Code Factory variant matches Direct LLM on key field extraction (KILE: 80.0%) while achieving the highest line item recognition accuracy (LIR: 80.4%). Security evaluation across 135 test cases demonstrates 96.7% accuracy on prompt injection detection and 87.5% on static code safety analysis with zero false positives.