Zekai Chen
Publications
MMFGU: Multimodal Federated Graph Unlearning
Multimodal federated graph learning enables clients to collaboratively train graph models over structural, textual, and visual signals without sharing private local data. However, the presence of heterogeneous multimodal content also makes unlearning requests more frequent and fine-grained: users may delete accounts or interactions, remove a particular image or text while retaining the associated entity, or revoke the learned correspondence between retained modalities or graph attributes. Existing federated graph unlearning mainly handles entity/relation or client removal and cannot directly satisfy these multimodal requests. They introduce three challenges: removing only the requested information without damaging retained content, preventing the target from being recovered through remaining modalities or graph neighborhoods, and stopping related traces on other clients from re-entering the global model after aggregation. To address them, we propose \textsc{\textbf{MMFGU}}, a multimodal federated graph unlearning framework built around target-specific representation decoupling. \textsc{MMFGU} maps heterogeneous requests into unified target carriers, decouples requested representations while anchoring retained semantics, exposes and repairs propagated residuals with lightweight probes, and selectively purges affected clients through compact prototype and response signals. Experiments show that \textsc{MMFGU} effectively removes requested information, preserves retained graph utility, and achieves a $\boldsymbol{41.5\times}$ speedup over full retraining.
FedOGL: Combating Catastrophic Forgetting in Federated Open-World Multimodal Graph Learning
Federated graph learning enables collaborative training over decentralized graph data without sharing raw graph information. As such risks evolve, clients must learn emerging classes from private multimodal graph streams, retain historical categories, and reject samples outside the known class space. In this setting, clients must learn emerging classes from private multimodal graph streams while preserving historical categories and rejecting samples outside the current known class space. The core challenge is catastrophic forgetting, which in federated multimodal graphs is not merely a classifier-level failure: old knowledge can be erased through modality-semantic overwriting, topology-induced structural erosion, and federated memory fragmentation. To address this challenge, we propose \textbf{FedOGL}, a semantic-structural memory preservation framework. On the client side, FedOGL preserves historical decision behavior through replay and task-start distillation, while protecting graph-propagation memory via projection onto a globally shared structure basis. On the server side, FedOGL maintains and transfers compact category prototypes to facilitate cross-client knowledge sharing without exposing raw graph data. Extensive experiments demonstrate that, compared with the best-performing baselines, FedOGL reduces performance degradation caused by catastrophic forgetting by \textbf{42.67\%}, while maintaining or improving performance on downstream tasks.
OpenRTAG: A Comprehensive Benchmark for Robust Text-Attributed Graph Learning under Data Quality Degradation
Text-attributed graphs (TAGs) are an important graph data form that combine relational structure with rich node text. However, real-world TAGs are often imperfect, with quality issues arising from text, structure, and labels, and typically manifesting as sparsity, noise, and imbalance. These dimensions define nine representative degradation scenarios that can substantially affect TAG learning. Although prior studies have explored specific mitigation strategies, existing evidence remains fragmented across degradation types, datasets, tasks, and model families, leaving TAG robustness insufficiently understood. To address this gap, we present OpenRTAG, a robustness benchmark for text-attributed graph learning. OpenRTAG organizes TAG quality issues into a unified 3 * 3 taxonomy and supports standardized evaluation across nine TAG datasets and three downstream tasks. It systematically evaluates scenario validity and model sensitivity, compares traditional GNNs, LLM-GNNs, and a representative GFM, investigates the effectiveness, efficiency, and robustness of scenario-matched baselines, and further examines model behavior under composite degradation scenarios. OpenRTAG provides a standardized testbed for understanding robustness in TAG learning under realistic low-quality settings.
The Patient is not a Moving Document: A World Model Training Paradigm for Longitudinal EHR
Large language models (LLMs) trained with next-word-prediction have achieved success as clinical foundation models. Representations from these language backbones yield strong linear probe performance across biomedical tasks, suggesting that patient semantics emerge from next-token prediction at scale. However, this paradigm treats patients as a document to be summarized rather than a dynamical system to be simulated; a patient's trajectory emerges from their state evolving under interventions and time, requiring models that simulate dynamics rather than predict tokens. To address this, we introduce SMB-Structure, a world model for structured EHR that grounds a joint-embedding prediction architecture (JEPA) with next-token prediction (SFT). SFT grounds our model to reconstruct future patient states in token space, while JEPA predicts those futures in latent space from the initial patient representation alone, forcing trajectory dynamics to be encoded before the next state is observed. We validate across two large-scale cohorts: Memorial Sloan Kettering (23,319 oncology patients; 323,000+ patient-years) and INSPECT (19,402 pulmonary embolism patients). Using a linear probe evaluated at multiple points along the disease trajectory, we demonstrate that our training paradigm learns embeddings that capture disease dynamics not recoverable by autoregressive baselines, enabling SMB-Structure to achieve competitive performance on complex tasks characterized by high patient heterogeneity. Model weights are available at https://huggingface.co/standardmodelbio/SMB-v1-1.7B-Structure.
LION: A Clifford Neural Paradigm for Multimodal-Attributed Graph Learning
Recently, the rapid advancement of multimodal domains has driven a data-centric paradigm shift in graph ML, transitioning from text-attributed to multimodal-attributed graphs. This advancement significantly enhances data representation and expands the scope of graph downstream tasks, such as modality-oriented tasks, thereby improving the practical utility of graph ML. Despite its promise, limitations exist in the current neural paradigms: (1) Neglect Context in Modality Alignment: Most existing methods adopt topology-constrained or modality-specific operators as tokenizers. These aligners inevitably neglect graph context and inhibit modality interaction, resulting in suboptimal alignment. (2) Lack of Adaptation in Modality Fusion: Most existing methods are simple adaptations for 2-modality graphs and fail to adequately exploit aligned tokens equipped with topology priors during fusion, leading to poor generalizability and performance degradation. To address the above issues, we propose LION (c\underline{LI}ff\underline{O}rd \underline{N}eural paradigm) based on the Clifford algebra and decoupled graph neural paradigm (i.e., propagation-then-aggregation) to implement alignment-then-fusion in multimodal-attributed graphs. Specifically, we first construct a modality-aware geometric manifold grounded in Clifford algebra. This geometric-induced high-order graph propagation efficiently achieves modality interaction, facilitating modality alignment. Then, based on the geometric grade properties of aligned tokens, we propose adaptive holographic aggregation. This module integrates the energy and scale of geometric grades with learnable parameters to improve modality fusion. Extensive experiments on 9 datasets demonstrate that LION significantly outperforms SOTA baselines across 3 graph and 3 modality downstream tasks.