Yonghong Tian
Publications
UniWorld-View: Large-Baseline View Synthesis via Video Diffusion Models
The abundance of casually captured monocular videos and images on social media provides a valuable source for immersive content creation, where generating novel views from such sparse observations can greatly enhance user experiences. However, producing photorealistic and geometrically consistent views with precise camera control remains challenging when input coverage is extremely limited. Reconstruction-based approaches such as NeRF and 3D Gaussian Splatting (3DGS) deteriorate severely under sparse inputs and fail to explicitly handle occlusions. Generative methods ease data requirements but still struggle with large-baseline view synthesis due to inaccurate or implicit geometric guidance. To overcome these limitations, we introduce UniWorld-View, a unified framework for controllable large-baseline novel view synthesis from monocular inputs. UniWorld-View integrates explicit 3D guidance with generative diffusion modeling to enable precise camera control and geometrically consistent view generation. The geometric guidance is obtained through an occlusion-aware point cloud rendering strategy that resolves visibility ambiguities and provides accurate priors for diffusion-based synthesis. By coupling this rendering strategy with powerful video diffusion backbones, UniWorld-View achieves high-fidelity novel view generation even under extreme camera motions and wide-baseline changes, and can further provide multi-view videos for downstream dynamic 3DGS reconstruction. Experiments on the WorldScore benchmark and zero-shot NVS benchmarks demonstrate the effectiveness of UniWorld-View in controllability, geometric consistency, and visual fidelity.
Agentic reinforcement learning empowers next-generation chemical language models for molecular design and synthesis
Language models are revolutionizing the biochemistry domain, assisting scientists in drug design and chemical synthesis with high efficiency. Yet current approaches struggle between small language models prone to hallucination and limited knowledge retention, and large cloud-based language models plagued by privacy risks and high inference costs. To bridge this gap, we introduce ChemCRAFT, a novel framework leveraging agentic reinforcement learning to decouple chemical reasoning from knowledge storage. Instead of forcing the model to memorize vast chemical data, our approach empowers the language model to interact with a sandbox for precise information retrieval. This externalization of knowledge allows a locally deployable small model to achieve superior performance with minimal inference costs. To enable small language models for agent-calling ability, we build an agentic trajectory construction pipeline and a comprehensive chemical-agent sandbox. Based on sandbox interactions, we constructed ChemToolDataset, the first large-scale chemical tool trajectory dataset. Simultaneously, we propose SMILES-GRPO to build a dense chemical reward function, promoting the model's ability to call chemical agents. Evaluations across diverse aspects of drug design show that ChemCRAFT outperforms current cloud-based LLMs in molecular structure analysis, molecular optimization, and synthesis pathway prediction, demonstrating that scientific reasoning is not solely an emergent ability of model scale, but a learnable policy of tool orchestration. This work establishes a cost-effective and privacy-preserving paradigm for AI-aided chemistry, opening new avenues for accelerating molecular discovery with locally deployable agents. Code available at https://github.com/HowardLi1984/ChemCraft.