Yang Liu
Publications
PathMem: Toward Cognition-Aligned Memory Transformation for Pathology MLLMs
Computational pathology demands both visual pattern recognition and dynamic integration of structured domain knowledge, including taxonomy, grading criteria, and clinical evidence. In practice, diagnostic reasoning requires linking morphological evidence with formal diagnostic and grading criteria. Although multimodal large language models (MLLMs) demonstrate strong vision language reasoning capabilities, they lack explicit mechanisms for structured knowledge integration and interpretable memory control. As a result, existing models struggle to consistently incorporate pathology-specific diagnostic standards during reasoning. Inspired by the hierarchical memory process of human pathologists, we propose PathMem, a memory-centric multimodal framework for pathology MLLMs. PathMem organizes structured pathology knowledge as a long-term memory (LTM) and introduces a Memory Transformer that models the dynamic transition from LTM to working memory (WM) through multimodal memory activation and context-aware knowledge grounding, enabling context-aware memory refinement for downstream reasoning. PathMem achieves SOTA performance across benchmarks, improving WSI-Bench report generation (12.8% WSI-Precision, 10.1% WSI-Relevance) and open-ended diagnosis by 9.7% and 8.9% over prior WSI-based models.
Streaming Hallucination Detection in Long Chain-of-Thought Reasoning
Long chain-of-thought (CoT) reasoning improves the performance of large language models, yet hallucinations in such settings often emerge subtly and propagate across reasoning steps. We suggest that hallucination in long CoT reasoning is better understood as an evolving latent state rather than a one-off erroneous event. Accordingly, we treat step-level hallucination judgments as local observations and introduce a cumulative prefix-level hallucination signal that tracks the global evolution of the reasoning state over the entire trajectory. Overall, our approach enables streaming hallucination detection in long CoT reasoning, providing real-time, interpretable evidence.