Yuqing Wang
Publications
MedGuideX: Internalizing Decision Logic from Executable Guidelines into Large Language Models for Clinical Reasoning
Clinical practice guidelines (CPGs) encode evidence-based decision logic that clinicians apply by evaluating patient variables, conditional criteria, and recommendation rules. However, existing methods often use CPGs as free-text training data or retrieval sources, underutilizing their procedural decision structure. To better exploit this structure, we introduce a guideline-derived training pipeline that transforms CPG recommendations into executable clinical decision logic and uses it to generate factual and counterfactual question-answering data. Theses data teach models both guideline-supported decisions and how decisions change under different patient conditions. Post-training a medical LLM on the generated data yields MedGuideX. Across four clinical reasoning benchmarks, MedGuideX achieves a 10.28% relative improvement in average accuracy. Physician evaluation further shows that MedGuideX better recovers clinician authored reasoning steps and produces physician-preferred rationales in faithfulness, validity, completeness, and clarity. Overall, our results show that executable decision logic from CPGs can be transformed into scalable supervision for building reliable medical LLMs.
PersonaDual: Balancing Personalization and Objectivity via Adaptive Reasoning
As users increasingly expect LLMs to align with their preferences, personalized information becomes valuable. However, personalized information can be a double-edged sword: it can improve interaction but may compromise objectivity and factual correctness, especially when it is misaligned with the question. To alleviate this problem, we propose PersonaDual, a framework that supports both general-purpose objective reasoning and personalized reasoning in a single model, and adaptively switches modes based on context. PersonaDual is first trained with SFT to learn two reasoning patterns, and then further optimized via reinforcement learning with our proposed DualGRPO to improve mode selection. Experiments on objective and personalized benchmarks show that PersonaDual preserves the benefits of personalization while reducing interference, achieving near interference-free performance and better leveraging helpful personalized signals to improve objective problem-solving.
PersonaDual: Balancing Personalization and Objectivity via Adaptive Reasoning
As users increasingly expect LLMs to align with their preferences, personalized information becomes valuable. However, personalized information can be a double-edged sword: it can improve interaction but may compromise objectivity and factual correctness, especially when it is misaligned with the question. To alleviate this problem, we propose PersonaDual, a framework that supports both general-purpose objective reasoning and personalized reasoning in a single model, and adaptively switches modes based on context. PersonaDual is first trained with SFT to learn two reasoning patterns, and then further optimized via reinforcement learning with our proposed DualGRPO to improve mode selection. Experiments on objective and personalized benchmarks show that PersonaDual preserves the benefits of personalization while reducing interference, achieving near interference-free performance and better leveraging helpful personalized signals to improve objective problem-solving.