Ping He
Publications
SE(3)-MeanFlow: Few-Step Protein Backbone Generation on Lie Groups
Generative modeling of protein backbones promises the de novo design of proteins with prescribed structural and functional properties. Existing diffusion and flow-matching models produce high-quality backbones on SE(3)^N, but inference requires numerically integrating an ODE over hundreds of network evaluations, each involving a Lie group exponential map - a bottleneck for high-throughput design campaigns. We introduce SE(3)-MeanFlow, a few-step generative framework that extends MeanFlow from Euclidean space to the Lie group geometry of protein frames. Working natively in the Lie algebra so(3) and in R^3, we derive closed-form average-velocity identities for rotations and translations, giving simulation-free training targets. We further introduce an SE(3) alpha-Flow objective that removes the Jacobian-vector product from the rotation branch and serves as a warm-up stage, after which training switches to a small-t stabilized MeanFlow loss that is used for the remainder of pretraining and for rectification-based post-training. In protein backbone generation, SE(3)-MeanFlow matches or exceeds flow-matching baselines that use several times more sampling steps, and its advantage widens in the few-step regime, where rectification lets it lead at every matched budget - at a modest cost in diversity.
Visko Orbis 1.0: A Live Model for Real-Time Interactive Long Video Generation
We present Visko Orbis 1.0, a Live Model for real-time, interactive long-video generation. Users can change the prompt at any moment during generation, and the update becomes visible in real time. Visko Orbis 1.0 supports long-form text-to-video, image-to-video, and video continuation, with multilingual prompts and prompt switching while generation is in progress. A bounded multi-scale memory preserves subjects, scenes, and style across chunks, sustaining hour-scale rollouts without evident quality or color drift. Built on a distilled chunk-wise streaming generator and a streaming video upscaler, Visko Orbis 1.0 delivers real-time 4K video generation at 24 FPS using an optimized GPU serving engine. In long-form Arena comparisons, Visko Orbis 1.0 obtains the highest overall-preference and temporal-stability ratings among state-of-the-art real-time interactive video-generation systems.